The Campaign is the core cooperative game mode in Back 4 Blood. By default, the Campaign is broken up into four Acts, ten Chapters and 33 Missions.
With the River of Blood expansion the Campaign has be expanded to a total of six Acts, twelve Chapters and 44 Missions.
Players can either start from the beginning of an Act or dive into a specific Chapter or Mission depending on their personal progression within the Campaign.
The Campaign can be played on four different difficulties: Recruit, Veteran, Nightmare and No Hope.
On Recruit difficulty, all Missions can be accessed via Checkpoints once they have been cleared at least once by the player.
The Mission Checkpoints on higher difficulties are far more stretched out, resulting into a greater challenge to clear an Act in a playthrough alongside various other obstacles.
The mode can be played with a pre-made team, online matchmaking, solo via the Training Mode or alone by starting the game in Offline mode.
Playing the game online allows players to form teams from the following platforms:
- PC (Epic Games Store, Microsoft Store, Steam, Xbox PC Gamepass)
- PlayStation
- Xbox
If players want to play with another across platforms the game offers this activity via the 
"Crossplay enabled"-option.
Recruit[]
Recruit difficulty
| “ | This ain't no cakewalk, but everyone has to learn the ropes. Cleaners have increased health, damage, and ammo capacity. |
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Recruit is the lowest difficulty and is the base difficulty for Supply Points calculation. The difficulty is best suited for players who are either new to Back 4 Blood or zombie first-person horde shooters in general.
The challenges this difficulty poses can be overcome without any specific decks or organization.
Veteran[]
Veteran difficulty
| “ | You know what you're doing. Gear up and get out there. Solid teamwork and custom decks will help you face the challenges ahead. Cleaners have small bonues to health, damage, and ammo capacity. |
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Veteran is the medium difficulty and offers more Supply Points than the Recruit difficulty. Veteran difficulty is best suited for players who are already familiar with the gameplay and decks of Back 4 Blood or zombie first-person horde shooters in general.
The challenges this difficulty poses can be overcome without any specific decks but requires organization and self-awareness of threats.
Nightmare[]
Nightmare difficulty
| “ | You might just be crazy enough to pull it off. Cleaners take increased Trauma damage and have 1 less Life. |
„ |
Nightmare offers even more Supply Points than the Recruit and Veteran difficulties.
Nightmare difficulty is best suited for players who no longer find any challenge on Veteran difficulty, have unlocked a high range of cards, have very good knowledge of Mission and gameplay, and are competent individually and as a team.
This level of difficulty requires that each individual on the team is familiar with the mechanics and Mission flow, and is able to form a synergy within the team using their decks to increase the chances of survival.
No Hope[]
No Hope difficulty
| “ | Bring custom decks, strong coordination and your best crew or don't plan to get anywhere in this difficulty. Modifiers: No Respawn Points, Lives don't recover, Roaming Bosses |
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No Hope is the newest and currently the highest difficulty of the game.
It has been added as a free update alongside the Tunnels of Terror expansion DLC that got implemented on April 12, 2022 with Patch 1.07.
This difficulty is aimed towards elite players to grant them a far more challenging experience.
Clearing the entire Campaign on this difficulty will reward players with the Grisly End banner.
Act 1[]
The Devil's Return[]
The Devil's Return is the first Chapter of Act 1. It consists of four Missions:
Search and Rescue[]
Search and Rescue is the second Chapter of Act 1. It consists of three Missions:
The Dark Before the Dawn[]
The Dark Before the Dawn is the third Chapter of Act 1. It consists of two Missions:
Blue Dog Hollow[]
Blue Dog Hollow is the fourth and the final Chapter of Act 1. It consists of four Mission:
Act 2[]
The Armory[]
The Armory is the first Chapter of Act 2. It consists of two Missions:
Plan B[]
Plan B is the second Chapter of Act 2. It consists of five Missions:
Job 10:22[]
Job 10:22 is the third and final Chapter of Act 2. It consists of three Missions:
Act 3[]
Dr. Rogers' Neighborhood[]
Dr. Rogers' Neighborhood is the first Chapter of Act 3. It consists of five Missions:
Remnants[]
Remnants is the second and final chapter of Act 3 . It consists of four missions:
Act 4[]
The Abomination[]
The Abomination is the only chapter of Act 4 and the final Mission of Back 4 Blood.
Act 5[]
Act 5 has been introduced with the second Expansion Pack, Children of the Worm, for Back 4 Blood.
It consists of one Chapter and six Missions.
Players who either own the expansion themselves or have at least one player on their team who has purchased this content can jump into this Act. Furthermore, players do not need to have completed any of the previous Acts to be able to enter Act 5. Only the restrictions mentioned above are in effect.
As the Ridden Hives in the Tunnels of Terror expansion were already excluded from matchmaking via Quickplay, this rule also applies to Act 5, as this content is tied to the respective expansion.
This Act also includes so-called Duffel Bags, which can be obtained exclusively in this part of the campaign. They act as interactive free loot boxes that you can find within the Missions and are rewarded with a random reward after successful completion.
These contain eleven Cards, Burn Cards, and two Outfits.
12:7 Dan[]
12:7 Dan is the only Chapter of Act 5. It consists of six Missions:
Act 6[]
Act 6 is the latest Campaign content which has been implemented with the third and final expansion of the Annual Pass, River of Blood.
It consists of one Chapter and five Missions.
River of Blood[]
River of Blood is the only Chapter of Act 6. It consists of five Missions:
